• Galactokinase 1PIE from Lactococcus lactis
• References
• Galactokinase Reaction
• Galactokinase Regulation
• Slides

References:

1.) Holden, HM, Thoden, JB, Timson, DJ, Reece, RJ. Galactokinase: structure, function, and role in type II galactosemia. Cellular and Molecular Life Sciences, 2004, (16):19-20.

2.) Holden, HM, Thoden, JB. Molecular structure of galactokinase. The Journal of Biological Chemistry, 2003, (35)33305-11.

3.) Holm, L, Rosenström, P. Dali server: conservation mapping in 3D. Nucl. Acids Res., 2010, (38)W545-549.

4.) Huang, M, Li, X, Zou, J, Timson, DJ. Role of Arg228 in the Phosphorylation of Galactokinase: The Mechanism of GHMP Kinases by Quantum Mechanics / Molecular Mechanics Studies. Biochemistry, 2013, (28):4858-68.

4.) Singh, R, Ram, J, Kaur, G, Prasad, R. Galactokinase deficiency induced cataracts in Indian infants: identification of 4 novel mutations in GALK gene. Current Eye Research, 2012, (10): 949-54.

5.) Thoden, JB, Kim J, Raushel FM, Holden HM. Structural and kinectic studies of sugar binding to galactose mutarotase from Lactococcus lactis. The Journal of Biological Chemistry, 2002, (47):45458-65.

6.)  Hartley A, Glynn SE, Barynin V, Baker PJ, Sedelnikova SE, Verhees C, de Geus D, van der Oost J, Timson DJ, Reece RJ, Rice DW. Substrate specificity and mechanism from the structure of Pyrococcus furiosus galactokinase. Journal of Molecular Biology, 2004, (2):387-98.

7.) Sellick, CA, Reece, RJ. Eukaryotic transcription factors as direct nutrient sensors. Trends in Biochemical Sciences, 2005, (7)405-12.

8.) Sil, AK, Alam, S, Xin, P, Ma, L, Morgan, M, Lebo, CM, Woods, MP, Hopper, JE. Molecular Cell Biology, 1999, (11)7828-40.