1. PDB ID: 1IYT
Crescenzi O, Tomaselli S,Guerrini R, Salvadori S, D’Ursi AM, Temussi PA, Picone D (2002). Solution Structure of the Alzheimer amyloid beta-peptide (1-42) in an apolar environment. Similarity with a virus fusion domain. The Protein Data Bank. EUR.J.BIOCHEM., 269:5642-5648. doi:10.2210/pdb1iyt/pdb
2. The Uniprot Consortium (2010). A4_HUMAN. The Universal Protein Resource (UniProt). Accession number: P05067
3. Zheng Hui, Koo Edward H(2006). The amyloid precursor protein: beyond amyloid. Molecular Neurodegeneration, 1:5. doi:10.1186/1750-1326-1-5.
4. Rossjohn J, Cappai R, Feil SC, Henry A, McKinstry WJ, Galatis D, Hesse L, Malthaup G, Beyreuther G,Masters CL, Parker MW (1999). Crystal structure of the N-terminal, Growth factor-like domain of Alzheimer amyloid precursor protein. Nat.Stru.Biol.,6:327-331. doi:10.1038/7562
5. Barnham KJ, McKinstry WJ,Multhaup G, Galatis D, Morton CJ, Curtain CC, Williamson NA, White AR, Hinds MG, Norton RS,Beyreuther K, Masters CL, Parker MW, Cappai R (2003). Structure of the Alzheimer’s disease amyloid precursor protein cepper binding domain. J.Biol.Chem., 278:17401-17407. doi: 1074/jbc.M3006629200
6. Dahms SO, Hoefgen S, Roeser D, Schlott B, Guhrs KH, Than ME (2010). Structure of the Heparin-induced E1-Dimer of the Amyloid Precursor Protein (APP). Proc.Natl.Acad.Sci.USA,107:5381-5386. doi:10.1073/pnas.0911326107.
7. Yongcheng Wang, Ya Ha(2004). The X-Ray Structure of an Antiparallel Dimer of the Human Amyloid Precursor Protein E2 Domain. Molecular Cell, 15:343-353.doi: 10.1016/j.molcel.2004.06.037
8. Shecter Y (1986). Selective oxidation and reduction of methionine residues in peptides and proteins byoxygen exchange between sulfoxide and sulfide. J.Biol.Chem., 261:66-70. PubMed PMID: 3001062
9. Hynes TR, Randal M, Kennedy LA, Eigenbrot C,Kossiakoff AA (1990). X-Ray Crystal Structure of the Protease Inhibitor Domain of Alzheimer’s Amyloid & Protein Precursor. Biochemistry:29(43):10018-22. doi:10.1021/bi00495a002
10. Beher D, Hesse L, Masters CL, Multhaup G (1996). Regulation of Amyloid Protein Precursor (APP) Binding to Collagen and Mapping of theBinding Sites on APP and Collagen Type I. J.Biol.Chem.,271:1613-20. doi:10.1074/jbc.271.3.1613
11. Walter J, Schindzielorz A, Hartung B, Haass C(2000). Phosphorylation of the β-Amyloid Precursor Protein at the Cell Surface by Ectocasein Kinases 1 and 2. J.Biol.Chem.,4:275(31):23523-9. doi:10.1074/jbc.M002850200
12. Haass C, Selkoe DJ (2007).Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer’s amyloid β-peptide.Molecular Cell Biology, 8:101-112.doi: 10.1038/nrm2101
13. Fortini ME (2002). γ-Secretase-mediated proteolysis in cell-surface-receptor signaling. Molecular Cell Biology, 3:673-684. doi: 10.1038/nrm910
14. Burgos PV, Mardones GA,Rojas AL, daSilva LLP, Prabhu Y, Hurley JH (2010). Sorting of the Alzheimer’s Disease Amyloid Precursor Protein Mediated by the AP-4 Complex. Developmental Cell, 18:425-436. doi:10.1016/j.devcel.2010.01.015
15. Luhrs T, Ritter C, Adrian M, Riek-Loher D, Bohrmann B, Dobeli H, Schubert D, Riek R (2005). 3D structure of Alzheimer’s amyloid- (1-42) fibrils. PNAS,102(48):17342-17347. doi:10.1073_pnas.0506723102
16. Citron M, Olterdorf T, Haass C, McConlogue L, Hung AY, Seubert P, Vigo-Pelfrey C, Lieberburg I, Selkoe DJ (1992). Mutation of the β-amyloid precursor protein in familial Alzheimer’s disease increases β-protein production. Nature, 360:672-674.doi:10.1038/3606672a0
17. Hoopes JT, Liu X, Demeler B, Folta-Stogniew E, LiC, Ha Y (2009). Structural characterization of the E2 domain of APL-1, aCaenorhabditis elegans homolog of human amyloid precursor protein, and its heparin binding site. J.Biol.Chem.,285(3):2165-73. doi: 10.1074/jbc.M109.018432
18. Patterson D, Feightner JW,Garcia A, Hsiung GYR, MacKnight C, Sadovnick AD (2008). Diagnosis and treatmentof dementia: 1. Risk assessment and primary prevention of Alzheimer disease. Canadian Medical Association Journal,26:178(5):548-56. doi: 10.1503/cmaj.070796